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5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages

ClearNote Health
February 2, 2026

Pilot study demonstrating changes in DNA hydroxymethylation enable detection of multiple cancers in plasma cell-free DNA

ClearNote Health
February 2, 2026

Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA

ClearNote Health
February 2, 2026

A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation

ClearNote Health
February 2, 2026

The Cell Type-Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia

ClearNote Health
February 2, 2026

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer

ClearNote Health
February 2, 2026

Epigenomic Blood-Based Early Detection of Pancreatic Cancer Employing Cell-Free DNA

ClearNote Health
February 2, 2026

Plasma cell-free DNA hydroxymethylation profiling reveals anti-PD-1 treatment response and resistance biology in non- small cell lung cancer

ClearNote Health
February 2, 2026

Analytical Validation of an Early Detection Pancreatic Cancer Test Using 5-Hydroxymethylation Signatures

ClearNote Health
February 2, 2026

5-hydroxymethylcytosine analysis reveals stable epigenomic changes in tumor tissue that enable cancer detection in cell-free DNA

ClearNote Health
January 30, 2026
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The Virtuoso platform is for research use only. Not for use in diagnostic procedures. The Avantect Pancreatic and Ovarian Cancers Tests are early detection tests. The tests do not establish a diagnosis of pancreatic cancer or ovarian cancer, respectively, and results should be considered in the context of other clinical criteria.

Cancer statistics quoted on this website are taken from the CDC and SEER websites, 2025 data.

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